Hvilken rolle har HMO?

Human Milk Oligosakkarider

Amming har vært forbundet med redusert risiko for diaré og luftveisinfeksjoner hos spedbarn.1,2 HMO kan delvis være årsaken til den beskyttende effekten som morsmelk gir. Studier tyder på at HMO i morsmelk har en viktig rolle i å støtte barnets immunforsvar.3-6

Referanser:

  1. Horta BL, Victora CG. Short-term effects of breastfeeding: a systematic review on the benefits of breastfeeding on diarrhoea and pneumonia mortality [internet]. World health organisation; 2013 [cited 2017; Dec 11]. Available from http://apps.who.int/iris/bitstream/10665/95585/1/9789241506120_eng.pdf.
  2. Victora C, Bahl R, Barros A, Franca G, Horton S, Krasevec J et al. Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect. Lancet. 2016 Feb;387:475-90.
  3. Bode L. The functional biology of human milk oligosaccharides. Early Hum Dev. 2015 Nov; 91(11):619-22.
  4. Donovan SM, Comstock SS. Human milk oligosaccharides influence neonatal mucosal and systemic immunity. Ann Nutr Metab. 2016 Jan;69(Suppl. 2):41-51.
  5. Newburg DS, Ruiz-Palacios GM, Morrow AL. Human milk glycans protect infants against enteric pathogens. Annu Rev Nutr. 2005 Jul;25:37-58.
  6. Morrow AL, Ruiz-Palacios GM, Jiang X, Newburg DS. Human-milk glycans that inhibit pathogen binding protect breast-feeding infants against infectious diarrhea. J Nutr. 2005 May;135(5):1304-7.