Hva skiller HMO fra GOS/FOS?

Human Milk Oligosakkarider

HMO, de komplekse strukturene som er unike i morsmelk, er strukturelt forskjellige fra de mindre komplekse oligosakkaridene, galaktooligosakkarider (GOS) og fructooligosakkarider(FOS), som i dag er tilsatt i noen morsmelkerstatninger. HMO har flere strukturspesifikke fordeler og gir flere fordeler for immunsystemet enn GOS/FOS.1-4

Referanser:

  1. Bode L. Human milk oligosaccharides: every baby needs a sugar mama. Glycobiology. 2012 Apr;22(9):1147-62.
  2. Comstock SS, Li M, Wang M, Monaco MH, Kuhlenschmidt TB, Kuhlenschmidt MS et al. Dietary human milk oligosaccharides but not prebiotic oligosaccharides increase circulating natural killer cell and mesenteric lymph node memory T cell populations in noninfected and rotavirus-infected neonatal piglets. J Nutr. 2017 Jun;147(6):1041-7.
  3. Goehring KC, Marriage BJ, Oliver JS, Wilder JA, Barrett EG, Buck RH. Similar to those who are breastfed, infants fed a formula containing 2′-fucosyllactose have lower inflammatory cytokines in a randomized controlled trial. J Nutr. 2016 Dec;146(12):2559-66.
  4. Hoeflinger JL, Davis SR, Chow J, Miller MJ. In vitro impact of human milk oligosaccharides on Enterobacteriaceae growth. J Agric Food Chem. 2015 Mar;63(12):3295-302.